Updated on June 4, 2026
| Post | Incumbent | Status | Year Appointed |
|---|---|---|---|
| American Tourism, Exceptionalism, and Values | Nick Adams | Other | 2026 |
| APEC Senior Official | Casey Mace | Career | 2025 |
| AUKUS Senior Advisor | Matthew D. Steinhelfer | Other | 2023 |
| Best Future Generations | Charles J. Harder | Other | 2025 |
| Combat HIV/AIDS Globally | Johnny Figueroa | Other | |
| Global Partnerships | Thomas Debass | Other | 2025 |
| Greenland | Jeff Landry | Other | 2026 |
| Holocaust Issues | Ellen Germain | Career | 2021 |
| Latin America | Mauricio Claver-Carone | Other | 2025 |
| Middle East | Massad Boulos | Other | 2025 |
| Middle East | Steve Witkoff | Other | 2025 |
| Monitor and Combat Anti-Semitism | Yehouda Kaploun | Other | 2025 |
| Special Missions | Richard Grenell | Other | 2025 |
| United Kingdom | Mark Burnett | Other | 2025 |